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Leonberger Polyneuropathy (LPN)
In this edition of Genome Barks we hear from Dr. Kari Ekenstedt who discusses Leonberger Polyneuropathy (LPN). Through her research Dr. Ekenstedt, along with a team of researchers at the University of Minnesota, the University of Bern, and the University of California San Diego, has identified a genetic mutation that points to the early onset of inherited LPN. In identifying this genetic mutation, Dr. Ekenstdet has been able to develop a genetic test for the leonberger breed. By testing leonbergers, an early diagnosis can be made and carriers of the mutation can be identified for breeding purposes.
Hypertrophic Osteodystrophy (HOD) and Legg-Calve-Perthes (LCP)
In this edition of Genome Barks we bring you an interview with Dr. Alison Starr, a scientific investigator at the Clemson Canine Genetics Research Group, which studies hereditary diseases in the domestic dog. Dr. Starr has received funding from the AKC Canine Health Foundation and her current research is focused on the development of genetic tests to help predict and screen for hereditary diseases.
In this podcast Dr. Starr discusses her study of Hypertrophic Osteodystrophy (HOD), a bone disease that usually affects young, rapidly growing, large breed dogs. Specifically, she is looking at HOD in Irish Setters. Additionally, Dr. Starr discusses her study of Legg-Calve-Perthes (LCP), a disease that results in the abnormal deformity of the ball of the hip joint and usually occurs in young miniature and small breeds of dogs. Specifically, she is looking at LCP in West Highland White Terriers and other Terrier breeds. For both HOD and LCP, Dr. Starr is hoping to discover the gene or genes responsible for these diseases so that genetic tests might be developed as a tool for producing better and healthier dogs.
Podcast on Genetics of Canine Behavior
In this edition of Genome Barks we bring you and interview with Dr. Mark Neff, scientific investigator and Director of program for canine health and performance at the Van Andel Research Institute. Dr. Neff has received funding from the AKC Canine Health Foundation and his current research is focused on neurological and behavioral disorders in the dog.
In this podcast Dr. Neff discusses how researchers are learning about the genes responsible for behaviors like pointing and herding and how understanding the principals of the mind can help them understand the intrinsic reward system that motivates dogs to do what they do.
Podcast on Bioinformatics
In this edition of Genome Barks we bring you an interview with Dr. Elinor Karlsson with the Broad Institute and the Sebeti Lab at Harvard. Dr. Karlsson has focused her research on the genetic cause of disease, including diseases associated with coat color traits such as ridgelessness in the Rhodesian Ridgeback and behavioral traits such as aggression.
In this podcast Dr. Karlsson discusses the technique of genome wide mapping; her research on canine compulsive disorder; the discovery of the gene for flank sucking in the Doberman Pinscher; and the implications of her research for human psychiatric disorders.
Podcast on Canine Compulsive Disorder
In this edition of Genome Barks we bring you an interview with Dr. Elinor Karlsson with the Broad Institute and the Sebeti Lab at Harvard. Dr. Karlsson has focused her research on the genetic cause of disease, including diseases associated with coat color traits such as ridgelessness in the Rhodesian Ridgeback and behavioral traits such as aggression.
In this podcast Dr. Karlsson discusses the technique of genome wide mapping; her research on canine compulsive disorder; the discovery of the gene for flank sucking in the Doberman Pinscher; and the implications of her research for human psychiatric disorders.
Podcast on Cryptorchidism and Cranial Cruciate Ligament Disease
In this edition of Genome Barks, we bring you and interview with Dr. Max Rothschild,
distinguished professor of agriculture and life sciences and director of the
Center for Integrated Animal Genomics at the Iowa State University College of Veterinary Medicine.
Funded by the AKC Canine Health Foundation primarily for his research in cryptorchidism,
Dr. Rothschild’s areas of research interest are gene mapping, reproduction and immunogenetics
of swine, new statistical methods to evaluate animals and gene identification in dogs.
Podcast on Coat Color Research
In this edition of Genome Barks, we bring you an interview with Dr. Sheila Schmutz a professor at the University of Saskatchewan. Funded in small part by the AKC Canine Health Foundation, Dr. Schmutz’s canine research has focused on coat color genetics.
Dr. Schmutz discusses the challenges of studying coat color, whether diseases are associated with coat color, and gives advice about coat color to those seeking a new puppy.
Podcast on Emergency and Critical Care
In this edition of Genome Barks, we bring you an interview with Dr. Gary Stamp, Executive Director of the Veterinary Emergency and Critical Care Society. Dr. Stamp served as commander of the United States Army Veterinary command until 1999 when he retired from active duty.
Dr. Stamp discusses how much first aid training dog owners should have, when emergency veterinary care is necessary, and how to select an emergency service.
Advantages of Purebred Dog Research
In this edition of Genome Barks, we welcome C.A. Sharp, President of the Australian Shepherd Health
and Genetics Institute, an organization dedicated to sharing knowledge about the genetics of the breed.
C.A. is also a prolific writer on canine health.
In this podcast C.A. discusses the reasons why purebred dogs are good research models;
why purebred dogs are helpful to human medicine and to veterinary medicine for all dogs;
and the need to participate in research by providing DNA samples.
Major Histiocompatability Complex
In this edition of Genome Barks, we welcome Dr. Lorna Kennedy, a member of the faculty of the University of Manchester Center for Integrated Genomic Medical Research in the United Kingdom. Dr. Kennedy has received funding from the AKC Canine Health Foundation for her work in the genetics of hypothyrodism, immune mediated hemolytic anemia and anal furunculosis.
These diseases are all associated with changes in an area of the canine genome called the Major Histiocompatability Complex (MHC). In this podcast, Dr. Kennedy discusses the MHC, autoimmune diseases, her research on these diseases and similarities to human conditions.
Shar Pei Fever
In this edition of Genome Barks, we welcome Mia Olsson a doctoral student at Uppsala University in Sweeden. Ms. Olsson discusses Shar Pei Fever and her research on the condition. Shar Pei Fever is a recurring fever-like condition that is similar to an auto-inflammatory condition in humans. Ms. Olsson is part of an international research team from Uppsala University and the Broad Institute of MIT and Harvard who discovered the gene associated with the condition.
Humane Fund Awards for Canine Excellence
In this edition of Genome Barks, we welcome Dr. Anne Hubbs, the Health Committee Chair of the Golden Retriever Club of America (GRCA). GRCA and the Golden Retriever Foundation have supported CHF-approved research with more than $300,000 in sponsorships since 1995. Dr. Hubbs discusses the Golden Retriever lovers’ dedication to canine health and some of the stories that motivated them to support health research, some of the top health concerns in the breed and their participation in the Canine Health Information Center (CHIC).
ACE Award Winner Taffy
We welcome the 2008 ACE winner for Search and Rescue, the Bloodhound Taffy and her handler, Doug Williams. Lee Arnold, Chairman of the AKC Canine Health Foundation, and Mr. Williams discuss Taffy’s accomplishments, school visits, criminal tracking, and community outreach.
Golden Retriever Lover's Commitment to Health
In this edition of Genome Barks, we welcome Dr. Anne Hubbs, the Health Committee Chair of the Golden Retriever Club of America (GRCA). GRCA and the Golden Retriever Foundation have supported CHF-approved research with more than $300,000 in sponsorships since 1995. Dr. Hubbs discusses the Golden Retriever lovers’ dedication to canine health and some of the stories that motivated them to support health research, some of the top health concerns in the breed and their participation in the Canine Health Information Center (CHIC).
Podcast on Dermatomyositis
In this edition of Genome Barks, we welcome Dr. Leigh Anne Clark, a member of the faculty at Clemson University. Dr. Clark’s research has focused on canine genetic disease. In this podcast, we discuss Dr. Clark’s work in dermatomyositis. Dr. Clark defines the disease, and discusses prevalence, clinical signs, and tips for breeders to help future generations.
Dr. Leigh Anne Clark attended Texas A&M University and received a Bachelor of Science degree in Biomedical Sciences in 2000. She subsequently entered graduate school and joined the Canine Genetics Laboratory in the College of Veterinary Medicine. Dr. Clark's thesis work concerned both the development of microsatellite DNA-based tools and pancreatic acinar atrophy in the German Shepherd Dog. She received a PhD in 2004 and remained in the Canine Genetics Laboratory for her postdoctoral work. Now an Assistant Professor of Genetics and Biochemistry at Clemson University, Dr. Clark's research continues to focus on canine inherited disease.
Podcast on Malignant Histiocytosis with Dr. Catherine André
In this edition of Genome Barks, we welcome Dr. Catherine André, a CHF-funded researcher and member of the faculty at the University of Rennes in France. Dr. André has received funding for her work in malignant histiocytosis in the Bernese Mountain Dog. Dr. André describes malignant histiocytosis, breeds at greater risk for this cancer, treatment possibilities, and also her research into ichthyosis in the Golden Retriever and some of her other projects.
Dr. Catherine André graduated with a PhD in molecular genetics and oncology at the Paris University in 1992. Since 1995 she has worked at the University of Rennes in France (CNRS) on canine genomics and genetics. She manages the canine genetics group at CNRS working on the search for the genetic basis of inherited diseases in canines and humans.
Genome Barks Podcast - Vaccinations with Dr. Kate Creevy
This week on Genome Barks, we welcome Dr. Kate Creevy, Assistant Professor in Small Animal Internal Medicine at the University of Georgia with a specialty in small animal medicine and infections disease. Dr. Creevy discusses the myths of vaccinations and infectious disease, susceptibility to vaccination reactions, regular vaccination schedules and the canine flu vaccine.
Dr. Creevy grew up in and around Cincinnati, Ohio, and attended Georgetown University for her undergraduate education. She earned her DVM from the University of Tennessee in 1998, and completed a rotating small animal internship at the University of Minnesota. She spent the next four years in private practice, initially in a small animal and exotics emergency-only practice in the Twin Cities, and then at Friendship Hospital for Animals, the only 24-hour general and specialty practice in Washington, DC. She joined the faculty at the University of Georgia in 2003 as an emergency medicine clinician, and subsequently completed both her residency in Small Animal Internal Medicine, and her Master’s degree in Infectious Disease at UGA. She is currently an Assistant Professor in Small Animal Internal Medicine at the University of Georgia.
Podcast About Veterinary Management of the Stud Dog with Dr. Lin Kauffman
A variety of conditions can affect the stud dog and his ability to produce viable sperm. It is important for a stud dog owner to understand the importance of cryptorchidism (retained testicle), testicular degeneration, testicular torsion and testicular trauma and what those conditions can do to their stud dog's breeding potential. Some of these conditions are temporary and some can have lasting outcomes. Azoospermia (a lack of sperm) can be noted during a routine breeding soundness examination and can be attributed to a variety of different causes.
Once again there may be some causes that are temporary while other causes may be permanent. Motility and morphology of sperm can also be assessed during a breeding soundness examination. Veterinarians can help counsel stud dog owners about potential genetic disease and infectious (venereal) disease testing that is now available for their stud dogs. It is also important that stud dog owners be aware of the various ways that stud dogs can be utilized in assisted canine reproduction (ex: fresh chilled semen shipment, cryopreservation of semen).
Canine prostate disease is a class of diseases that stud dog owners need to be aware of. There are distinct clinical signs to watch for in their stud dogs and veterinarians have specific tests to determine the difference between benign prostatic hyperplasia, infectious prostatitis, prostatic abscess and prostatic neoplasia (cancer). Some of these diseases carry specific treatment plans and good outcomes, where others carry a more somber outcome.
Genome Barks Podcast - Bartonella Infections with Dr. Ed Breitschwerdt
Podcast Released on Tick Borne Diseases
This week on Genome Barks, we welcome Dr. Ed Breitschwerdt, a specialist in internal medicine and infectious disease at North Carolina State University. Dr. Breitschwerdt has received funding from the Canine Health Foundation for various infectious diseases (visit www.caninehealthfoundation.org for more information on Dr. Breitschwerdt’s research) including Bartonella spp. In this podcast, Dr. Breitschwerdt describes Bartonella, explains what clinical signs to look for in a potentially ill animal, and also discusses the various research projects underway.
Genome Barks Podcast - Reponsible Breeding with Dr. Jerold Bell
American Kennel Club and Canine Health Foundation Release Podcast
about Responsible Breeding Practices
This week we welcome Dr. Jerold Bell, the Director of Clinical Veterinary Genetics Course at the Tufts Cummings School of Veterinary Medicine.
In this interview, Dr. Bell discusses why genetic testing is important,
describes the different types of genetic tests and how to best use the test results.
Genome Barks Podcast - One Health with Mike Sampson
American Kennel Club and AKC Canine Health Foundation Release Podcast
about Genetic Relationships of Purebred Dogs
This week Genome Barks welcomes Mike Sampson, an expert in emergency management and preparedness. An adjunct lecturer at the University of Tennessee in Knoxville, Mr. Sampson discusses the One Health concept and its implications to both human and veterinary research. Additional topics include public health as it relates to veterinary medicine and the detection and treatment of illness like SARS and the latest influenza virus, H1N1.
American Kennel Club and AKC Canine Health Foundation Release
Podcast
about Canine Nutrition
American Kennel Club and AKC Canine Health Foundation Release
Podcast
about Canine Nutrition
The AKC and Canine Health Foundation Genome Barks Podcast series welcomes
Dr. Deborah Greco, Senior Research Scientist at Nestle Purina PetCare Company.
Dr. Greco has spent her 30 years in practice studying endocrinology, reproduction and nutrition. In this interview, Dr. Greco discusses the art and science of supplementation and pro-biotics,
as well as optimum proteins and general nutrition
as they pertain
to developing and maintaining good haircoat.
Genome Barks Podcast - Canine Cancer Treatments with Dr. Jaime Modiano
American Kennel Club and AKC Canine Health Foundation Release Podcast
about Canine Cancer Treatments
Genome Barks welcomes Dr. Jaime Modiano, a member of the faculty of the College of Veterinary Medicine at the University of Minnesota.
Dr. Modiano has spent the last 15 years of his career looking at the mechanisms that are responsible for the origin and progression of canine cancer.
Dr. Modiano’s current research focuses on better cancer therapies,
singling out the canine immune system as a treatment for cancers that are
in the process of spreading to various regions of the body.
Genome Barks Podcast - Translational Medicine with Dr. Simon Gregory
American Kennel Club and AKC Canine Health Foundation Release Podcast about the Similarities between Human and Canine Disease
This week, the Genome Barks podcast series welcomes Dr. Simon Gregory, a human cancer researcher at Duke University. Dr. Gregory is working with Dr. Matthew Breen of North Carolina State University on brain tumors. This podcast discusses
the similarities between human and caine disease.
Genome Barks Podcast - Common Poisons with Dr. John Tegzes
American Kennel Club and AKC Canine Health Foundation Release Podcast
about Common Poisons
This week on Genome Barks, we welcome Dr. John Tegzes of Western University of Health Sciences in Pomona, California. Dr. Tegzes is Professor of Toxicology and has specialized in clinical toxicology. In this podcast, we discuss the number one poison to watch for, as well as the dangers of chocolate and plants. Dr. Tegzes also talks about the warning signs that your animal has been poisoned.
Genome Barks Podcast - Canine Lymphoma Cell Lines as
a Research Tool with Dr. Steven Suter
American Kennel Club and AKC Canine Health Foundation Release Podcast
about Canine Lymphoma Research
The American Kennel Club and the AKC Canine Health Foundation are pleased to debut the next podcast in the Genome Barks series.
This week, Genome Barks and Lee Arnold, Vice Chairman of the AKC Canine Health Foundation, welcome Dr. Steven Suter of North Carolina State University, who is currently working to develop canine lymphoma cell lines. These cell lines will greatly enhance lymphoma research by providing a research tool to study the disease on a cellular level and determine the molecular behavior of lymphoma.
